Information

Flower identification: Moscow, Russia


I found this plant near the MSU, Moscow, Russia. Could someone help me to identify it?


It looks very similar to Cephalaria gigantea.


Plant Biology at Belyaev Conference – 2017

This thematic issue of BMC Plant Biology continues the series of BioMed Central special post-conference issues presenting materials from the conferences on bioinformatics and systems biology collectively known as BGRSSB (Bioinformatics of Genome Regulation and StructureSystems Biology) held in Novosibirsk. It contains the papers discussed at the international conference “Belyaev Readings - 2017” (BR-2017) (http://conf.bionet.nsc.ru/belyaev100/en) and Young Scientists School “Systems Biology and Bioinformatics - 2017” (SBB-2017) (http://conf.bionet.nsc.ru/sbb2017/en/).

The year 2017 marks the 100-th anniversary since birth of Full Member of the USSR Academy of Sciences, Professor Dmitry K. Belyaev (1917–1985), an outstanding scientist, evolutionist and geneticist. In view of this memorable date, the Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences (ICG SB RAS) held the international Belyaev Conference on Genetics and Evolution (Novosibirsk, August 7-10, 2017).

The memorial Belyaev conference-2017 continued traditions of BGRSSB and PlantGen conference series comprising several science sections including Plant Biology. Over the last two decades, since 1998, the BGRS/SB series gained a reputation as a prime meeting venue in Russia for biologists, computer scientists, mathematicians and biochemists working in the interdisciplinary systems biology field, now focusing more on computational plant biology.

The section on Plant Biology at Belyaev Conference-2017 was dedicated to genomic and post-genomic approaches to analysis of the organization of the plant genomes, the development of sequencing and genotyping applications for plants, with special emphasis to important crop cultivars.

Plant-Gen-2017 event in Almaty, Kazakhstan (http://primerdigital.com/PlantGen2017/en/) gathered both the international scientists and the Committee members of Plant Biology section of the Belyaev Conference-2017 from Novosibirsk, thus joining the research efforts two largest post-Soviet countries and ensuring the exchange of expertise in plant genetics. BMC Plant Biology published special thematic issue presenting materials of PlantGen-2017 event (https://bmcplantbiol.biomedcentral.com/articles/supplements/volume-17-supplement-1).

Previously published special issues of BMC Plant Biology and BMC Evol Biol covered the proceeding of BGRSSB-2016 conference and SBB-2015 School in Novosibirsk [1,2,3,4] as well as BGRSSB-2014 event (https://bmcgenomics.biomedcentral.com/articles/supplements/volume-15-supplement-12).

In 2017, “Vavilov Journal of Selection and Breeding” published a series of memoirs publications about Prof. Belyaev (http://vavilov.elpub.ru/jour/issue/view/32/showToc). The article by V.K. Shumny [5] tells the history of Belyaev’s life, while other publications discuss importance of Belyaev’s work on the theory of evolution and domestication. The material on plant biology discussed at Belyaev conference-2017 were in part published in Russian at next issue of “Vavilov Journal of Selection and Breeding” (http://vavilov.elpub.ru/jour/issue/view/33/showToc).

Current issue extends the line of breakthrough publications on a variety of agricultural crops, including potato, flax and wheat, as well as highlights the area of pathogen resistance in plants.

Olesya Y. Shoeva and co-authors [6] systematically reviewed the environmental factors affecting anthocyanin biosynthesis pathway genes in plants. In various plants, relative strengths of selective pressure differ, with genes of dicots undergoing stronger pressure than in monocots, and in pollinator-dependent plants more than that in pollinator-independent species. This observation highlights an important role of insects-dependent pollination in the evolution of the anthocyanin biosynthesis gene network.

The research topics of next few papers consider agriculturally important features of higher plants. Wheat morphotypes with altered spike morphology associated with the development of supernumerary spikelets present an important genetic resource for studies on genetic regulation of inflorescence development.

Oxana B. Dobrovolskaya and colleagues [7] characterized diploid and tetraploid wheat lines of various non-standard spike morphotypes, which allowed for identification of a new mutant allele of the WHEAT FRIZZY PANICLE (WFZP) gene that determines spike branching in diploid wheat Ttiticum monococcum L. Supernumerary spikelets mutants represent an important genetic tool for research on the development of the wheat spikelet and for identification of genes that control meristem activities. Authors show that FRIZZY PANICLE and SHAM RAMIFICATION2 genes independently regulate differentiation of floral meristems in wheat.

Alexey A. Dmitriev and co-authors [8] considered pathogen resistance in flax (Linum usitatissimum L.), a crop plant used for fiber and oil production. Using high-throughput sequencing, the genes involved in the early defense response of flax against the fungus Fusarium oxysporum were identified. The changes in the expression of pathogenesis-related genes and genes involved in ROS production or related to cell wall biogenesis are reported.

The article by Alex V. Kochetov et al. [9] dissects major nematode resistance genes in the potato by comparative analysis of root transcriptomes of Solanum phureja genotypes with contrasting resistance to Globodera rostochiensis. It was shown earlier that nucleotide-binding site-leucine-rich repeat (NBS-LRR) genes compose the largest plant resistance gene family, accounting for about 80% of known resistance genes. Combination of transcriptomic analysis with data on predicted potato NBS-LRR-encoding genes considerably improved the results. Authors discussed candidate genes that provide S. phureja with strong resistance to the potato golden cyst nematode.

Saule Abugalieva and colleagues [10] performed taxonomic reassessment of the specimens of Allium subgenus Reticulatobulbosa collected in Central Asia according to the sequences of internally transcribes spacers and matK markers. Their analysis robustly confirmed the monophyletic origin of the Allium species. The study contributes to taxonomy clarification in Allium.

The article by Maria D. Logacheva et al. [11] discusses evolutionary events which shaped up the plastomes of polypod ferns (Polypodiales). Сhloroplast genomes (plastomes) of land plants are generally conserved, having slow rate of the sequence and structure evolution. The authors characterized plastid genomes of three species of Dryopteris, which is one of the largest fern genera, and performed comparative analysis of their chloroplast DNA enriched with available plastomes of Polypodiales, the most species-rich group of ferns. The authors argue that Inverted Repeats of Polypodiales plastomes are dynamic genetic system being constantly re-shuffled by gene loss, duplication and putative lateral transfer from mitochondria.

Ćilerdžić and colleagues [12] discuss the degradation of lignin by fungal enzymes. Structural component of plant biomass, lignocellulose, is the most abundant renewable resource in nature. Its delignification is critically dependent on white-rot fungi owing to their strong ligninolytic enzyme system. The authors consider the differences in ligninolytic potential of the fungal species and shortlist best candidates for engineering for a variety of biotechnological processes involving biotransformation of lignocellulose residues/wastes.

At the end of this Special Issue, two articles on the novel techniques for genetic analysis in plants are presented.

Satyvaldy Jatayev and co-authors [13] provided scientific community with an improve plant genotyping technique. Widespread introduction of both low- and high-throughput SNP-based genotyping systems formed a cornucopia of potential applications. In their paper, Jatayev et al. showcase cost-efficiency of Amplifluor-like (Amplification with fluorescence) system for SNP genotyping of plant genomes.

Finally, Bykova et al. [14] presented chip-based SNPs phenotyping of the resistance to spot blotch in barley. Spot blotch, caused by Cochliobolus sativus, is one of the most widespread and harmful diseases in barley. The study utilized 50 K Illumina Infinium iSELECT assay and spring barley core collection to identify three genomic loci conferring seedling resistance to two C. sativus.

We hope that that the readership of BMC Plant Biology would find this collection of papers interesting and useful.


References

Orlov YL, Baranova AV, Hofestadt R, Kolchanov NA. Computational genomics at BGRSSB-2016: introductory note. BMC Genomics. 201617(Suppl 14):996.

Orlov YL, Baranova AV, Markel AL. Computational models in genetics at BGRSSB-2016: introductory note. BMC Genet. 201617(Suppl 3):155.

Baranova AV, Orlov YL. Evolutionary biology at BGRSSB-2016. BMC Evol Biol. 201717(Suppl 1):21.

Orlov YL, Baranova AV, Salina EA. Computational plant bioscience at BGRSSB-2016: introductory note. BMC Plant Biol. 201616(Suppl 3):243.

Orlov YL, Baranova AV, Herbeck YE. Evolutionary biology at Belyaev conference - 2017. BMC Evol Biol. 201717(Suppl 2):260.

Orlov YL, Baranova AV, Tatarinova TV, Kolchanov NA. Genetics at Belyaev conference - 2017: introductory note. BMC Genet. 201718(Suppl 1):116.

Orlov YL, Baranova AV, Chen M, Salina EA. Plant biology at Belyaev conference - 2017. BMC Plant Biol. 201717(Suppl 2):257.

Dresvyannikova AE, Watanabe N, Muterko AF, Krasnikov AA, Goncharov NP, Dobrovolskaya OB. Characterization of a dominant mutation for the liguleless trait: Aegilopstauschiiliguleless (Lg t ). BMC Plant Biol. 201919(Suppl 1).

Dobrovolskaya OB, Amagai Y, Popova KI, Dresvyannikova AE, Martinek P, Krasnikov AA, Watanabe N. Genes WHEAT FRIZZY PANICLE and SHAM RAMIFICATION 2 independently regulate differentiation of floral meristems in wheat. BMC Plant Biol. 201717(Suppl 2):252. https://doi.org/10.1186/s12870-017-1191-3.

Dobrovolskaya O, Pont C, Sibout R, Martinek P, Badaeva E, Murat F, Chosson A, Watanabe N, Prat E, Gautier N, Gautier V, Poncet C, Orlov YL, Krasnikov AA, Bergès H, Salina E, Laikova L, Salse J. FRIZZY PANICLE drives supernumerary spikelets in bread wheat. Plant Physiol. 2015167(1):189–99. https://doi.org/10.1104/pp.114.250043.

Strygina KV, Khlestkina EK. Myc-like transcriptional factors in wheat: structural and functional organization of the subfamily I members. BMC Plant Biol. 201919(Suppl 1).

Gordeeva EI, Glagoleva AY, Kukoeva TV, Khlestkina EK, Shoeva OY. Purple-grained barley (Hordeumvulgare L.): marker-assisted development of NILs for investigating peculiarities of the anthocyanin biosynthesis regulatory network. BMC Plant Biol. 201919(Suppl 1).

Makarenko MS, Usatov AV, Tatarinova TV, Azarin KV, Logacheva MD, Gavrilova VA, Horn R. Characterization of the mitochondrial genome of the MAX1 type of cytoplasmic male-sterile sunflower. BMC Plant Biol. 201919(Suppl 1).

Dmitriev AA, Krasnov GS, Rozhmina TA, Zyablitsin AV, Snezhkina AV, Fedorova MS, Pushkova EN, Kezimana P, Novakovskiy RO, Povkhova LV, Smirnova MI, Muravenko OV, Bolsheva NL, Kudryavtseva AV, Melnikova NV. Flax (Linumusitatissimum L.) response to non-optimal soil acidity and zinc deficiency. BMC Plant Biol. 201919(Suppl 1).

Klepikova AV, Kulakovskiy IV, Kasianov AS, Logacheva MD, Penin AA. An update to database TraVA: organ-specific cold stress response in Arabidopsis thaliana. BMC Plant Biol. 201919(Suppl 1).

Doroshkov AV, Konstantinov DK, Afonnikov DA, Gunbin KV. The evolution of gene regulatory networks controlling Arabidopsis thaliana L. trichome development. BMC Plant Biol. 201919(Suppl 1).


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Editors

Andrei V. Vasiliev
Dr. Sci. (Biol.), Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia Department of Embryology, Lomonosov Moscow State University, Moscow, Russia

Irina Yu. Baklushinskaya
Dr. Sci. (Biol.), Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia
Yegor S. Vassetzky
Dr. Sci. (Biol.), CNRS UMR9018, Institut Gustave Roussy, Villejuif, France Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia

Yulia A. Kraus
PhD (Biol.), Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia

Igor I. Adameiko
Dr. Sci. (Biol.), Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden Laboratory of Embryogenesis Research, Medical University of Vienna, Austria
Yury D. Bogdanov
Dr. Sci. (Biol.), University of Southampton, Great Britain
Varvara E. Diakonova
Dr. Sci. (Biol.), Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia
Tatyana A. Ezhova
Dr. Sci. (Biol.), Moscow State University, Faculty of Biology, Department of Genetics, Moscow, Russia
Grigory N. Enikolopov
PhD (Biol.), Stony Brook University, Stony Brook, NY, USA Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA
Alexander V. Ereskovky
Dr. Sci. (Biol.), Mediterranean Institute of Marine and Terrestrial Biodiversity and Ecology (IMBE), Aix Marseille University, CNRS, IRD, Avignon Université, Marseille, France St.-Petersburg State University, Faculty of Biology, Department of Embryology Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia
Oleg A. Gusev
PhD (Biol.), Institute of Fundamental Medicine and Biology of Kazan Federal University RIKEN Innovation Center, Yokohama, Japan
Roman P. Kostyuchenko
PhD (Biol.), Saint-Petersburg State University, Faculty of Biology, Department of Embryology, Saint-Petersburg, Russia
Georgy S. Levit
Dr. Sci. (Biol.), Saint-Petersburg National Research University of Information Technology, Mechanics and Optics (ITMO), Saint-Petersburg, Russia
Victor S. Mikhailov
Dr. Sci. (Biol.), Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia
Galina E. Onischenko
Dr. Sci. (Biol.), Moscow State University, Faculty of Biology, Department of Cell Biology and Histology, Moscow, Russia
Daria V. Onitschouk
Dr. Sci. (Biol.), Department of Developmental Biology, Institute of Biology I, Faculty of Biology, University of Freiburg, Freiburg, Germany Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia
Nikolay D. Ozernyuk
Dr. Sci. (Biol.), Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia
Margarita V. Remizova
PhD (Biol.), Moscow State University, Faculty of Biology, Department of High Plants, Moscow, Russia
Sergei V. Rozhnov
Dr. Sci. (Biol.), Institute of Paleontology of the Russian Academy of Sciences, Moscow, Russia
Oleg L. Serov
Dr. Sci. (Biol.), Institute of Cytology and Genetics, Siberean Branch of the Russian Academy of Sciences, Novosibirsk, Russia
Alexei N. Tomilin
Dr. Sci. (Biol.), Institute of Cytology of the Russian Academy of Sciences, Saint-Petersburg, Russia
Andrey G. Zaraisky
Dr. Sci. (Biol.), Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Moscow, Russia

Maria A. Aleksandrova
Dr. Sci. (Biol.), Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia
Vsevolod Ya. Brodsky
Dr. Sci. (Biol.), Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia
Scott F. Gilbert
PhD, Professor of Biology Swarthmore, Pennsylvania, United States
Vladimir A. Golichenkov
Dr. Sci. (Biol.), Faculty of Biology, Moscow State University, Moscow, Russia
Eleonora N. Grigoryan
Dr. Sci. (Biol.), Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia
Victor B. Ivanov
Dr. Sci. (Biol.), Department of Root Physiology, Timiryazev Institute of Plant Physiology, Russian Academy of Sciences, Moscow, Russia
Alexey M. Kulikov
Dr. Sci. (Biol.), Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia
Irina V. Lyadova
Dr. Sci. (Med.), Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia
Alexander V. Markov
Dr. Sci. (Biol.), Lomonosov Moscow State University, Biological Faculty, Moscow, Russia
Alexey M. Olovnikov
PhD (Biol.), Institute of Biochemical Physics of the Russian Academy of Sciences, Moscow, Russia
Dmitri A. Sakharov
Dr. Sci. (Biol.), Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia
Natalya P. Sharova
Dr. Sci. (Biol.), Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia
Olga B. Simonova
Dr. Sci. (Biol.), Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia
Olga G. Stroeva
Dr. Sci. (Biol.), Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia
Victor S. Tarabykin
Dr. Sci. (Biol.), Institute of Cell Biology and Neurobiology, Charité, Berlin, Germany Lobachevsky State University of Nizhny Novgorod, Nizhny Novgorod, Russia
Mikhail V. Ugryumov
Dr. Sci. (Biol.), Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia
Suren M. Zakian
Dr. Sci. (Biol.), The Federal Research Center Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia
Igor S. Zakharov
Dr. Sci. (Biol.), Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia

Elena D. Gasilo
Dr. Sci. (Biol.), Koltzov Institute of Developmental Biology of the Russian Academy of Sciences, Moscow, Russia


Editors

Alexander A. Makarov
Dr. Sci. (Biol.), Prof., Full Member of the Russian Academy of Sciences, Engelhardt Institute of Molecular Biology, Moscow, Russia
DEPUTY EDITORS-IN-CHIEF
Vadim L. Karpov
Dr. Sci. (Biol.), Prof., Corresponding Member of the Russian Academy of Sciences, Engelhardt Institute of Molecular Biology, Moscow, Russia
Vladimir S. Prasolov
Dr. Sci. (Biol.), Prof., Engelhardt Institute of Molecular Biology, Moscow, Russia
EXECUTIVE EDITOR
Tatiana A. Pronina
Cand. Sci. (Biol.), All-Russian Institute for Scientific and Technical Information (VINITI), Moscow, Russia
EDITORIAL BOARD
Anna V. Baranova
Dr. Sci. (Biol.), Prof., George Mason University, School of Systems Biology, Fairfax, USA
Petr M. Chumakov
Dr. Sci. (Biol.), Prof., Corresponding Member of the Russian Academy of Sciences, Engelhardt Institute of Molecular Biology, Moscow, Russia
Vladimir G. Debabov
Dr. Sci. (Biol.), Prof., Full Member of the Russian Academy of Sciences, National Research Center &ldquoKurchatov Institute&rdquo &ndash Research Institute for Genetics and Selection of Industrial Microorganisms, Moscow, Russia
Olga A. Dontsova
Dr. Sci. (Biol.), Prof., Full Member of the Russian Academy of Sciences, Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia
Olga O. Favorova
Dr. Sci. (Biol.), Prof., Pirogov Russian National Research Medical University, Moscow, Russia
Aleksey V. Finkelshtein
Dr. Sci. (Phys.-Math.), Prof., Full Member of the Russian Academy of Sciences, Institute of Protein Research, Pushchino, Russia
Mikhail S. Gelfand
Dr. Sci. (Biol.), Prof., Institute for Information Transmission Problems, Moscow, Russia
Sofia G. Georgieva
Dr. Sci. (Biol.), Prof., Corresponding Member of the Russian Academy of Sciences, Institute of Gene Biology, Moscow, Russia
Marina B. Gottikh
Dr. Sci. (Сhem.), Prof., Belozersky Institute of Physico-Chemical Biology, Moscow, Russia
Vladimir A. Gvozdev
Dr. Sci. (Biol.), Prof., Full Member of the Russian Academy of Sciences, National Research Center &ldquoKurchatov Institute&rdquo &ndash Institute of Molecular Genetics, Moscow, Russia
Sergey N. Kochetkov
Dr. Sci. (Chem.), Prof., Full Member of the Russian Academy of Sciences, Engelhardt Institute of Molecular Biology, Moscow, Russia
Dmitry V. Kuprash
Dr. Sci. (Biol.), Prof., Corresponding Member of the Russian Academy of Sciences, Engelhardt Institute of Molecular Biology, Moscow, Russia
Olga I. Lavrik
Dr. Sci. (Chem.), Prof., Full Member of the Russian Academy of Sciences, Institute of Chemical Biology and Fundamental Medicine, Novosibirsk, Russia
Dmitry A. Los'
Dr. Sci. (Biol.), Prof., Corresponding Member of the Russian Academy of Sciences, Timiryazev Institute of Plant Physiology, Moscow, Russia
Sergey A. Lukyanov
Dr. Sci. (Biol.), Prof., Full Member of the Russian Academy of Sciences, Pirogov Russian National Research Medical University, Moscow, Russia
Sergey A. Nedospasov
Dr. Sci. (Biol.), Prof., Full Member of the Russian Academy of Sciences, Engelhardt Institute of Molecular Biology, Moscow, Russia
ADVISORY BOARD
Grigory N. Enikolopov
Cand. Sci. (Biol.), Prof., Cold Spring Harbor Laboratory, New York, USA
Andrei V. Gudkov
Dr. Sci. (Biol.), Prof., Roswell Park Cancer Institute, Buffalo, USA
Alexey S. Kondrashov
Cand. Sci. (Biol.), Prof., Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, USA Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow, Russia
Eugene V. Koonin
Cand. Sci. (Biol.), Prof., National Center for Biotechnology Information, Bethesda, USA
Julia G. Kzhyshkowska
Dr. Sci. (Biol.), Prof., Universität Heidelberg, Faculty of Medicine Mannheim and Clinic Mannheim, Germany
Inna N. Lavrik
Dr. Sci. (Biol.), Prof., Otto-von-Guericke-Universität Magdeburg, Translational Inflammation Research, Magdeburg, Germany Federal Research Center Institute of Cytology and Genetics, Novosibirsk, Russia
Ruslan M. Medzitov
Dr. Sci. (Biol.), Prof., Yale University, New Haven, USA
Sergei M. Mirkin
Dr. Sci. (Biol.), Prof., Tufts University, Medford, USA
Eugeny A. Nudler
Dr. Sci. (Biol.), Prof., NYU Langone Medical Center, Department of Biochemistry and Molecular Pharmacology, New York, USA Engelhardt Institute of Molecular Biology, Moscow, Russia
Eugene I. Rogaev
Dr. Sci. (Biol.), Prof., University of Massachusetts Medical School, Worcester, USA Vavilov Institute of General Genetics, Moscow, Russia
Alexander Y. Rudensky
Dr. Sci. (Biol.), Prof., Howard Hughes Medical Institute and Immunology Program at Sloan Kettering Institute, and Ludwig Center for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, USA
Michael Y. Sherman
Cand. Sci. (Biol.), Prof., Ariel University, Department of Molecular Biology, Ariel, Israel
Vasily M. Studitsky
Dr. Sci. (Biol.), Prof., Cancer Epigenetics Program, Fox Chase Cancer Center, Philadelphia, USA Biological Faculty, Moscow State University, Moscow, Russia
Yegor S. Vassetzky
Dr. Sci. (Biol.), Institut de Cancérologie Gustave Roussy, Signaling, Nuclei and Innovations in Oncology Unit, Villeiuif, France
Marat M. Yusupov
Dr. Sci. (Biol.), Prof., Institute of Genetics and of Molecular and Cellular Biology, Strasbourg, France Institute of Fundamental Medicine and Biology, Kazan (Volga) Federal University, Kazan, Russia


U.S. Department of the Treasury

Specially Designated Nationals List Update

The following individuals have been added to OFAC's SDN List:

CHERNYKH, Tatiana V (a.k.a. CHERNYKH, Tatiana) DOB 25 Sep 1972 nationality Russia Passport 712491743 (Russia) expires 17 Nov 2020 Foreign Relations Manager at Izhevsky Mekhanichesky Zavod JSC (individual) [UKRAINE-EO13661] (Linked To: IZHEVSKY MEKHANICHESKY ZAVOD JSC).

DEYNEGO, Vladyslav Nykolayevych (a.k.a. DEYNEGO, Vladislav Nykolayevich) DOB 12 Mar 1964 (individual) [UKRAINE-EO13660].

IOFFE, Eduard A (a.k.a. IOFFE, Eduard) DOB 07 Jun 1970 nationality Russia Passport 713023636 (Russia) expires 20 Jan 2021 Deputy General Director for Commercial Affairs at Kalashnikov Concern and Izhevsky Mekhanichesky Zavod JSC (individual) [UKRAINE-EO13661] (Linked To: KALASHNIKOV CONCERN Linked To: IZHEVSKY MEKHANICHESKY ZAVOD JSC).

KARAMYAN, Vakhtang (a.k.a. KARAMIAN, Vakhtang) DOB 19 Apr 1991 nationality Russia Passport 727409284 (Russia) expires 28 Mar 2023 Middle East Business Development Director at Kalashnikov Concern (individual) [UKRAINE-EO13661] (Linked To: KALASHNIKOV CONCERN).

KOFMAN, Aleksandr Igorevich (a.k.a. KOFMAN, Oleksandr) DOB 30 Aug 1977 (individual) [UKRAINE-EO13660].

KOZYAKOV, Serhiy (a.k.a. KOZYAKOV, Sergey a.k.a. KOZYAKOV, Sergey Yurievich) DOB 29 Sep 1982 (individual) [UKRAINE-EO13660].

NIKITIN, Vasiliy Aleksandrovich (Cyrillic: НИКИТИН, Василий Александрович) (a.k.a. NIKITIN, Vasily a.k.a. NIKITIN, Vasyl) DOB 25 Nov 1971 (individual) [UKRAINE-EO13660].

OLSSON, Sven Anders, Karl X Gustafs Gata 51, Helsingborg 252 40, Sweden DOB 1943 (individual) [UKRAINE-EO13661].

RODKIN, Andrei Nikolaevich (a.k.a. RODKIN, Andrei (Cyrillic: РОДКИН, Андрей) a.k.a. RODKIN, Andrey) DOB 23 Sep 1976 (individual) [UKRAINE-EO13660].

TABACHNYK, Dmytro Volodymyrovych (a.k.a. TABACHNIK, Dmitry a.k.a. TABACHNYK, Dmytriy) DOB 28 Nov 1963 (individual) [UKRAINE-EO13660].

TSYPLAKOV, Sergey Gennadevich (a.k.a. TSYPLAKOV, Gennady) DOB 01 May 1983 (individual) [UKRAINE-EO13660].

ZAKHARCHENKO, Vitaliy Yuriyovych DOB 20 Jan 1963 POB Kostiantynivka, Donetsk Region, Ukraine (individual) [UKRAINE-EO13660] (Linked To: YANUKOVYCH, Viktor Fedorovych).

The following entities have been added to OFAC's SDN List:

AKTSIONERNOE OBSCHESTVO 'YALTINSKAYA KINODSTUDIYA' (a.k.a. CJSC YALTA-FILM a.k.a. FILM STUDIO YALTA-FILM a.k.a. JOINT STOCK COMPANY YALTA FILM STUDIO a.k.a. JSC YALTA FILM STUDIO a.k.a. KINOSTUDIYA YALTA-FILM a.k.a. OAO YALTINSKAYA KINOSTUDIYA a.k.a. YALTA FILM STUDIO a.k.a. YALTA FILM STUDIOS), Ulitsa Mukhina, Building 3, Yalta, Crimea 298063, Ukraine Sevastopolskaya 4, Yalta, Crimea, Ukraine Registration ID 30993572 [UKRAINE-EO13685].

AVIA GROUP TERMINAL LIMITED LIABILITY COMPANY (a.k.a. AG TERMINAL OOO a.k.a. LLC AG TERMINAL a.k.a. OBSHCHESTVO S OGRANICHENNOI OTVETSTVENNOSTYU AVIA GRUPP TERMINAL (Cyrillic: ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ АВИА ГРУПП ТЕРМИНАЛ)), Ter. Aeroport Sheremetyevo, Khimki, Moscovskaya Oblast 141400, Russia [UKRAINE-EO13661] (Linked To: AVIA GROUP LLC).

CRIMEAN ENTERPRISE AZOV DISTILLERY PLANT (a.k.a. AZOVSKY LIKEROGORILCHANY ZAVOD, KRYMSKE RESPUBLIKANSKE PIDPRYEMSTVO a.k.a. AZOVSKY LIKEROVO-DOCHNY ZAVOD a.k.a. CRIMEAN REPUBLICAN ENTERPRISE AZOV DISTILLERY a.k.a. CRIMEAN REPUBLICAN ENTERPRISE AZOVSKY LIKEROVODOCHNY ZAVOD a.k.a. KRYMSKE RESPUBLIKANSKE PIDPRYEMSTVO AZOVSKY LIKEROGORILCHANY ZAVOD), Bud. 40 vul. Zaliznychna, Smt Azovske, Dzhankoisky R-N, Crimea 96178, Ukraine 40 Railway St., Azov, Dzhankoy District 96178, Ukraine 40 Zeleznodorozhnaya str., Azov, Jankoysky District 96178, Ukraine Registration ID 01271681 (Ukraine) [UKRAINE-EO13685].

FENTEX PROPERTIES LTD., Tortola, Virgin Islands, British [UKRAINE-EO13661].

INRESBANK OOO (a.k.a. INRESBANK LTD a.k.a. INVESTITSIONNY RESPUBLIKANSKI BANK OBSHCHESTVO S OGRANICHENNOI OTVETSTVENNOSTYU a.k.a. INVESTMENT REPUBLIC BANK LLC f.k.a. OOO KBK BANK), Ulitsa Bolshaya Semenovskaya, D. 32, Str. 1, Moscow 107023, Russia SWIFT/BIC INKKRUM1 alt. SWIFT/BIC IREPRUMM [UKRAINE-EO13661] (Linked To: SMP BANK).

JOINT STOCK COMPANY GENBANK (a.k.a. AKTSIONERNOE OBSHCHESTVO GENBANK (Cyrillic: АКЦИОНЕРНОЕ ОБЩЕСТВО ГЕНБАНК) a.k.a. CLOSED JOINT STOCK COMPANY GENBANK a.k.a. GENBANK, AO (Cyrillic: ГЕНБАНК, АО) a.k.a. JSC GENBANK), Ozerkovskaya Naberezhnaya 12, Moscow 115184, Russia Ulitsa Sevastopolskaya 13, Simferopol 295011, Ukraine SWIFT/BIC GEOORUMM Website www.genbank.ru Email Address [email protected] Registration ID 1137711000074 (Russia) [UKRAINE-EO13685].

JOINT STOCK COMPANY SEVASTOPOLSKY MORSKOY BANK (a.k.a. AKTSIONERNOE OBSHCHESTVO SEVASTOPOLSKIY MORSKOY BANK a.k.a. AO SEVASTOPOLSKIY MORSKOY BANK a.k.a. JSC SEVASTOPOLSKY MORSKOY BANK), 18a Brestska Street, Sevastopol, Crimea 99001, Ukraine 18/A Ulitsa Brestskaya, Sevastopol, Crimea 299001, Ukraine SWIFT/BIC MORKUAUK Website www.morskoybank.com Email Address [email protected] Registration ID 1149204013397 [UKRAINE-EO13685].

LERMA TRADING S.A., Calle 53a Este, Panama [UKRAINE-EO13661].

LTS HOLDING LIMITED (f.k.a. IPP-INTERNATIONAL PETROLEUM PRODUCTS LTD.), Rue du Conseil-General 20, Geneva 1204, Switzerland Tortola, Virgin Islands, British [UKRAINE-EO13661].

MAPLES SA, Boulevard Royal 25/B 2449, Luxembourg [UKRAINE-EO13661].

OAO VOLGOGRADNEFTEMASH (f.k.a. DOCHERNEE AKTSIONERNOE OBSHCHESTVO OTKRYTOGO TIPA VOLGOGRADNEFTEMASH ROSSIISKOGO AKTSIONERNOGO OBSHCHESTVA GAZPROM a.k.a. JSC VOLGOGRADNEFTEMASH a.k.a. OTKRYTOE AKTSIONERNOE OBSHCHESTVO VOLGOGRADNEFTEMASH (Cyrillic: ОТКРЫТОЕ АКЦИОНЕРНОЕ ОБЩЕСТВО ВОЛГОГРАДНЕФТЕМАШ)), 45 Ulitsa Elektrolesovskaya, Volgograd, Volgogradskaya Oblast 400011, Russia [UKRAINE-EO13661] (Linked To: STROYGAZMONTAZH).

OPEN JOINT STOCK COMPANY COMMERCIAL BANK VERKHNEVOLZHSKY (a.k.a. COMMERCIAL JOINT-STOCK BANK VERHNEVOLGSKY a.k.a. OAO KB VERKHNEVOLZHSKIY a.k.a. OJSC CB VERKHNEVOLZHSKY a.k.a. OTKRYTOE AKTSIONERNOE OBSHCHESTVO KOMMERCHESKIY BANK VERKHNEVOLZHSKIY a.k.a. PUBLIC COMMERCIAL JOINT-STOCK BANK VERHNEVOLZHSKY), Ulitsa Bratyev Orlovykh 1a, Rybinsk, Yaroslavskaya Oblast 152903, Russia Ulitsa Suvorova 39A, Sevastopol, Crimea 299011, Ukraine Pereulok Pionerskiy 5, Simferopol, Crimea 295011, Ukraine SWIFT/BIC VECARU21 alt. SWIFT/BIC VVBKRU2Y Website www.vvbank.ru Email Address [email protected] Registration ID 1027600000185 (Russia) [UKRAINE-EO13685].

OPEN JOINT STOCK COMPANY KRASNODAR REGIONAL INVESTMENT BANK (a.k.a. OAO KRAYINVESTBANK (Cyrillic: ОАО КРАЙИНВЕСТБАНК) a.k.a. OJSC KRAYINVESTBANK a.k.a. OTKRYTOE AKTSIONERNOE OBSHCHESTVO KRASNODARSKIY KRAEVOY INVESTITSIONNIY BANK (Cyrillic: ОТКРЫТОЕ АКЦИОНЕРНОЕ ОБЩЕСТВО КРАСНОДАРСКИЙ КРАЕВОЙ ИНВЕСТИЦИОННЫЙ БАНК)), Ulitsa Mira 34, Krasnodar 350063, Russia Ulitsa Bolshaya Morskaya 23, Sevastopol, Crimea 299011, Ukraine Ulitsa Dolgorukovskaya/Zhukovskogo/A. Nevskogo 1/1/6, Simferopol, Crimea 295000, Ukraine SWIFT/BIC KRRIRU22 Website www.kibank.ru Email Address [email protected] Registration ID 1022300000029 (Russia) All offices worldwide [UKRAINE-EO13685].

OTKRYTOE AKTSIONERNOE OBSHCHESTVO VNESHNEEKONOMICHESKOE OBEDINENIE TEKHNOPROMEKSPORT (a.k.a. JOINT STOCK COMPANY FOREIGN ECONOMIC ASSOCIATION TECHNOPROMEXPORT a.k.a. JOINT STOCK COMPANY FOREIGN ECONOMIC ASSOCIATION TEKHNOPROMEXPORT a.k.a. JSC TEKHNOPROMEXPORT a.k.a. JSC VO TEKHNOPROMEXPORT a.k.a. OJSC TECHNOPROMEXPORT a.k.a. OPEN JOINT STOCK COMPANY FOREIGN ECONOMIC ASSOCIATION TEKHNOPROMEXPORT a.k.a. VO TEKHNOPROMEKSPORT, OAO a.k.a. "JSC TPE"), d. 15 str. 2 ul. Novy Arbat, Moscow 119019, Russia Email Address [email protected] Registration ID 1067746244026 (Russia) Tax ID No. 7705713236 (Russia) Government Gazette Number 02839043 (Russia) [UKRAINE-EO13685].

PAO MOSOBLBANK (a.k.a. AKB MOSOBLBANK OAO a.k.a. AKTSIONERNY KOMMERCHESKI BANK MOSKOVSKI OBLASTNOI BANK OTKRYTOE AKTSIONERNOE OBSHCHESTVO a.k.a. PUBLIC JOINT STOCK COMPANY MOSCOW REGIONAL BANK), Ulitsa Semenovskaya B, D. 32, Str. 1, Moscow 107023, Russia SWIFT/BIC MOBKRUMM [UKRAINE-EO13661] (Linked To: SMP BANK).

RESORT NIZHNYAYA OREANDA (f.k.a. FEDERALNOE GOSUDARSTVENNOE BYUDZHETNOE UCHREZHDENIE SANATORI NIZHNYAYA OREANDA UPRAVLENIYA a.k.a. FEDERALNOE GOSUDARSTVENNOE BYUDZHETNOE UCHREZHDENIE SANATORI NIZHNYAYA OREANDA UPRAVLENIYA DELAMI PREZIDENTA ROSSISKOI FE a.k.a. FGBU SANATORI NIZHNYAYA OREANDA a.k.a. SANATORIUM NIZHNYAYA OREANDA), Pgt Oreanda, Dom 12, Yalta, Crimea 298658, Ukraine Resort Nizhnyaya Oreanda, Oreanda, Yalta 08655, Crimea Oreanda - 12, Yalta 298658, Crimea Website http://www.oreanda.biz Email Address [email protected] Registration ID 1149102054221 Tax ID No. 9103006321 Government Gazette Number 00705605 [UKRAINE-EO13685].

STATE CONCERN NATIONAL PRODUCTION AND AGRICULTURAL ASSOCIATION MASSANDRA (a.k.a. MASSANDRA NATIONAL INDUSTRIAL AGRARIAN ASSOCIATON OF WINE INDUSTRY a.k.a. MASSANDRA STATE CONCERN, NATIONAL PRODUCTION AND AGRARIAN UNION, OJSC a.k.a. NACIONALNOYE PROIZ-VODSTVENNO AGRARNOYE OBYEDINENYE MASSANDRA a.k.a. STATE CONCERN NATIONAL ASSOCIATION OF PRODUCERS MASSANDRA), 6, str. Mira, Massandra, Yalta 98600, Ukraine 6, Mira str., Massandra, Yalta, Crimea 98650, Ukraine Mira str, h. 6, Massandra, Yalta, Crimea 98600, Ukraine 6, Myra st., Massandra, Crimea 98650, Ukraine Website http://www.massandra.net.ua/ Email Address [email protected] Registration ID 00411890 (Ukraine) [UKRAINE-EO13685].

STATE ENTERPRISE FACTORY OF SPARKLING WINE NOVY SVET (a.k.a. DERZHAVNE PIDPRYEMSTVO ZAVOD SHAMPANSKYKH VYN NOVY SVIT a.k.a. GOSUDARSTVENOYE PREDPRIYATIYE ZAVOD SHAMPANSKYKH VIN NOVY SVET a.k.a. NOVY SVET WINERY a.k.a. NOVY SVET WINERY STATE ENTERPRISE a.k.a. STATE ENTERPRISE FACTORY OF SPARKLING WINES NEW WORLD a.k.a. ZAVOD SHAMPANSKYKH VYN NOVY SVIT, DP), 1 Shaliapin Street, Novy Svet Village, Sudak, Crimea 98032, Ukraine Bud. 1 vul. Shalyapina Smt, Novy Svit, Sudak, Crimea 98032, Ukraine 1 Shalyapina str. Novy Svet, Sudak 98032, Ukraine Website http://nsvet.com.ua/en/contacts Email Address [email protected] Registration ID 00412665 (Ukraine) [UKRAINE-EO13685].

STATE ENTERPRISE MAGARACH OF THE NATIONAL INSTITUTE OF WINE (a.k.a. AGROFIRMA MAGARACH NATSIONALNOGO INSTYTUTU VYNOGRADU I VYNA MAGARACH, DP a.k.a. DERZHAVNE PIDPRYEMSTVO AGROFIRMA MAGARACH NATSIONALNOGO INSTYTUTU VYNOGRADU I VYNA MAGARACH a.k.a. GOSUDARSTVENOYE PREDPRIYATIYE AGRO-FIRMA MAGARACH NACIONALNOGO INSTITUTA VINOGRADA I VINA MAGARACH a.k.a. MAGARACH AGRICULTURAL COMPANY OF NATIONAL INSTITUTE OF WINE AND GRAPES MAGARACH a.k.a. STATE ENTERPRISE AGRICULTURAL COMPANY MAGARACH NATIONAL INSTITUTE OF VINE AND WINE MAGARACH), Bud. 9 vul. Chapaeva, S.Viline, Bakhchysaraisky R-N, Crimea 98433, Ukraine 9 Chapayeva str., Vilino, Bakhchisaray Region, Crimea 98433, Ukraine 9 Chapayeva str., Vilino, Bakhchisarayski district 98433, Ukraine 9, Chapaeva Str., Vilino, Bakhchisaray Region, Crimea 98433, Ukraine Website http://magarach-institut.ru/ Email Address [email protected] Registration ID 11231070006000476 (Ukraine) Government Gazette Number 31332064 (Ukraine) [UKRAINE-EO13685].

STATE ENTERPRISE UNIVERSAL-AVIA (a.k.a. CRIMEAN STATE AVIATION ENTERPRISE UNIVERSAL-AVIA a.k.a. GOSUDARSTVENNOE UNITARNOE PREDPRIYATIE RESPUBLIKI KRYM UNIVERSAL a.k.a. GOSUDARSTVENNOE UNITARNOE PREDPRIYATIE RESPUBLIKI KRYM UNIVERSAL-AVIA a.k.a. GOSUDARSTVENOYE PREDPRIYATIYE UNIVERSAL-AVIA a.k.a. UNIVERSAL-AVIA, CRIMEA STATE AVIATION ENTERPRISE a.k.a. UNIVERSAL-AVIA, GUP RK), 5, Aeroflotskaya Street, Simferopol, Crimea 95024, Ukraine Registration ID 1159102026742 Tax ID No. 9102159300 Government Gazette Number 00830954 [UKRAINE-EO13685].

TRANSSERVICE LLC (a.k.a. LIMITED LIABILITY COMPANY TRANSSERVIS a.k.a. OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTYU TRANSSERVIS (Cyrillic: OБЩЕСТВО С OГРАНИЧЕННОЙ OТВЕТСТВЕННОСТЬЮ ТРАНССЕРВИС) a.k.a. OOO TRANSSERVIS (Cyrillic: ООО ТРАНССЕРВИС)), D. 35 Prospekt Gubkina, Omsk, Omskaya Oblast 664035, Russia [UKRAINE-EO13661] (Linked To: TRANSOIL).

WHITE SEAL HOLDINGS LIMITED, 115 Spyrou Kyprianou Avenue, Limassol 3077, Cyprus [UKRAINE-EO13661].


Editors

DEPUTY EDITORS-IN-CHIEF
Irina V. Goldenkova-Pavlova
Dr. Sci. (Biol.), Institute of Plant Physiology, Russian Academy of Sciences, Moscow, Russia
Ilya V. Seregin
Dr. Sci. (Biol.), Istitute of Plant Physiology, Moscow, Russia

EDITORIAL BOARD
Nikolaus Amrhein
Dr. Sci. (Biol.), Institute of Microbiology, Zurich, Switzerland
Suleyman I. Allakhverdiev
Dr. Sci. (Biol.), Institute of Plant Physiology, Russian Academy of Sciences, Moscow, Russia
Klaus Appenroth
PhD, Institute of General Botany and Plant Physiology, Friedrich-Schiller University, Jena, Germany
Nikolay P. Bityutskii
Dr. Sci. (Biol.), St. Petersburg State University, St. Petersburg, Russia
Thomas Börner
Dr. Sci. (Biol.), Institute of Biology/Genetics, Humboldt University, Berlin, Germany
Alexander A. Bulychev
Dr. Sci. (Biol.), Moscow State University, Moscow, Russia
Elena V. Deineko
Dr. Sci. (Biol.), Institute of Cytology and Genetics, Novosibirsk, Russia
Christian Dumas
Dr. Sci. (Biol.), French National Institute for Agricultural Research, Lyon, France
Michael A. Hall
Dr. Sci. (Biol.), Aberystwyth University, Aberystwyth, United Kingdom
Andrei U. Igamberdiev
Dr. Sci. (Biol.), Memorial University of Newfoundland, Corner Brook, Canada
Yury V. Ivanov
Cand. Sci. (Biol.), Institute of Plant Physiology, Russian Academy of Sciences, Moscow, Russia
Olga V. Karpova
Dr. Sci. (Biol.), Moscow State University, Moscow, Russia
Emil E. Khavkin
Dr. Sci. (Biol.), All-Russia Institute of Agricultural Biotechnology, Moscow, Russia
Yury E. Kolupaev
Dr. Sci. (Biol.), Kharkov University, Kharkov, Ukraine
Vladimir D. Kreslavski
Dr. Sci. (Biol.), Institute of Fundamental Problems of Biology, Russian Academy of Sciences, Pushchino, Moscow Region, Russia
Victor V. Kusnetsov
Dr. Sci. (Biol.), Institute of Plant Physiology, Moscow, Russia
Nikolai A. Laman
Dr. Sci. (Biol.), Institute of Experimental Botany, National Academy of Sciences, Minsk, Belarus
Trofim Kh. Maksimov
Dr. Sci. (Biol.), North-Eastern Federal University, Yakutsk, Russia
Alex M. Nosov
Dr. Sci. (Biol.), Moscow State University, Moscow, Russia
Alex V. Nosov
Dr. Sci. (Biol.), Institute of Plant Physiology, Moscow, Russia
Ralf Oelmüller
Dr. Sci. (Biol.), Friedrich Schiller University, Jena, Germany
Bart Panis
Dr. Sci. (Biol.), Biodiversity International, Leuven, Belgium
Hugh Pritchard
Dr. Sci. (Biol.), Royal Botanic Gardens, Kew, United Kingdom
Georgy A. Romanov
Dr. Sci. (Biol.), Institute of Plant Physiology, Moscow, Russia
Praveen K. Saxena
Dr. Sci. (Biol.), University of Guelph, Guelph, Canada
Henk Schat
Wageningen University, Wageningen, Netherlands
Thomas Schmülling
Dr. Sci. (Biol.), Freie Universität Berlin, Berlin, Germany
Vijay P. Singh
PhD, University of Allahabad, Allahabad, India
Alexei E. Solovchenko
Dr. Sci. (Biol.), Moscow State University, Moscow, Russia
Kazimierz Strzalka
Dr. Sci. (Biol.), Jagiellonian University, Krakow, Poland
Alexander F. Titov
Dr. Sci. (Biol.), Karelian Research Centre, Petrozavodsk, Russia
Tatsuya Tomo
Dr. Sci. (Biol.), Tokyo University of Science, Tokyo, Japan
Marina S. Trofimova
Dr. Sci. (Biol.), Institute of Plant Physiology, Moscow, Russia
Igor D. Volotovsky
Dr. Sci. (Biol.), Institute of Biophysics and Cell Engineering, Minsk, Belarus
Pavel Yu. Voronin
Dr. Sci. (Biol.), Institute of Plant Physiology, Moscow, Russia
Yuri N. Zhuravlev
Dr. Sci. (Biol.), Federal Scientific Center of the East Asia Terrestrial Biodiversity, Vladivostok, Russia


Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR

Background Understanding the influence of genetic variants on DNA methylation is fundamental for the interpretation of epigenomic data in the context of disease. There is a need for systematic approaches not only for determining methylation quantitative trait loci (methQTL) but also for discriminating general from cell-type-specific effects.

Results Here, we present a two-step computational framework MAGAR, which fully supports identification of methQTLs from matched genotyping and DNA methylation data, and additionally the identification of quantitative cell-type-specific methQTL effects. In a pilot analysis, we apply MAGAR on data in four tissues (ileum, rectum, T-cells, B-cells) from healthy individuals and demonstrate the discrimination of common from cell-type-specific methQTLs. We experimentally validate both types of methQTLs in an independent dataset comprising additional cell types and tissues. Finally, we validate selected methQTLs (PON1, ZNF155, NRG2) by ultra-deep local sequencing. In line with previous reports, we find cell-type-specific methQTLs to be preferentially located in enhancer elements.

Conclusions Our analysis demonstrates that a systematic analysis of methQTLs provides important new insights on the influences of genetic variants to cell-type-specific epigenomic variation.


Microbial metabolic response to winter warming stabilizes soil carbon

College of Resources and Environmental Sciences, Key Laboratory of Plant-Soil Interactions, Ministry of Education, National Academy of Agriculture Green Development, China Agricultural University, Beijing, PR China

Key Laboratory of Ecosystem Network Observation and Modeling, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences (CAS), Beijing, PR China

Jing Tian, College of Resources and Environmental Sciences Key Laboratory of Plant-Soil Interactions, Ministry of Education, National Academy of Agriculture Green Development, China Agricultural University, 100193, Beijing, PR China.

Guirui Yu, Key Laboratory of Ecosystem Network Observation and Modeling, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences (CAS), 100101, Beijing, PR China.

Key Laboratory of Ecosystem Network Observation and Modeling, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences (CAS), Beijing, PR China

Geography, College of Life and Environmental Sciences, University of Exeter, Exeter, UK

Key Laboratory of Ecosystem Network Observation and Modeling, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences (CAS), Beijing, PR China

Key Laboratory of Soil Resource Sustainable Utilization for Commodity Grain Bases of Jilin Province, College of Resource and Environmental Science, Jilin Agricultural University, Changchun, China

Department of Sustainable Agriculture Sciences, Rothamsted Research, Harpenden, UK

Institute for Environmental Genomics, Department of Microbiology and Plant Biology and School of Civil Engineering and Environmental Sciences, University of Oklahoma, Norman, OK, USA

Earth and Environmental Sciences, Lawrence Berkeley National Laboratory, Berkeley, CA, USA

Department of Soil Science of Temperate Ecosystems, University of Göttingen, Göttingen, Germany

Agro-Technological Institute, RUDN University, Moscow, Russia

Institute of Environmental Sciences, Kazan Federal University, Kazan, Russia

College of Resources and Environmental Sciences, Key Laboratory of Plant-Soil Interactions, Ministry of Education, National Academy of Agriculture Green Development, China Agricultural University, Beijing, PR China

Key Laboratory of Ecosystem Network Observation and Modeling, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences (CAS), Beijing, PR China

Jing Tian, College of Resources and Environmental Sciences Key Laboratory of Plant-Soil Interactions, Ministry of Education, National Academy of Agriculture Green Development, China Agricultural University, 100193, Beijing, PR China.

Guirui Yu, Key Laboratory of Ecosystem Network Observation and Modeling, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences (CAS), 100101, Beijing, PR China.

Geography, College of Life and Environmental Sciences, University of Exeter, Exeter, UK

Carbon Management Centre, SRUC-Scotland's Rural College, Edinburgh, UK

College of Resources and Environmental Sciences, Key Laboratory of Plant-Soil Interactions, Ministry of Education, National Academy of Agriculture Green Development, China Agricultural University, Beijing, PR China

Key Laboratory of Ecosystem Network Observation and Modeling, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences (CAS), Beijing, PR China

Jing Tian, College of Resources and Environmental Sciences Key Laboratory of Plant-Soil Interactions, Ministry of Education, National Academy of Agriculture Green Development, China Agricultural University, 100193, Beijing, PR China.

Guirui Yu, Key Laboratory of Ecosystem Network Observation and Modeling, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences (CAS), 100101, Beijing, PR China.

Key Laboratory of Ecosystem Network Observation and Modeling, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences (CAS), Beijing, PR China

Geography, College of Life and Environmental Sciences, University of Exeter, Exeter, UK

Key Laboratory of Ecosystem Network Observation and Modeling, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences (CAS), Beijing, PR China

Key Laboratory of Soil Resource Sustainable Utilization for Commodity Grain Bases of Jilin Province, College of Resource and Environmental Science, Jilin Agricultural University, Changchun, China

Department of Sustainable Agriculture Sciences, Rothamsted Research, Harpenden, UK

Institute for Environmental Genomics, Department of Microbiology and Plant Biology and School of Civil Engineering and Environmental Sciences, University of Oklahoma, Norman, OK, USA

Earth and Environmental Sciences, Lawrence Berkeley National Laboratory, Berkeley, CA, USA

Department of Soil Science of Temperate Ecosystems, University of Göttingen, Göttingen, Germany

Agro-Technological Institute, RUDN University, Moscow, Russia

Institute of Environmental Sciences, Kazan Federal University, Kazan, Russia

College of Resources and Environmental Sciences, Key Laboratory of Plant-Soil Interactions, Ministry of Education, National Academy of Agriculture Green Development, China Agricultural University, Beijing, PR China

Key Laboratory of Ecosystem Network Observation and Modeling, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences (CAS), Beijing, PR China

Jing Tian, College of Resources and Environmental Sciences Key Laboratory of Plant-Soil Interactions, Ministry of Education, National Academy of Agriculture Green Development, China Agricultural University, 100193, Beijing, PR China.

Guirui Yu, Key Laboratory of Ecosystem Network Observation and Modeling, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences (CAS), 100101, Beijing, PR China.

Geography, College of Life and Environmental Sciences, University of Exeter, Exeter, UK

Carbon Management Centre, SRUC-Scotland's Rural College, Edinburgh, UK

Jing Tian and Ning Zong contributed equally to this work.

Abstract

Current consensus on global climate change predicts warming trends with more pronounced temperature changes in winter than summer in the Northern Hemisphere at high latitudes. Moderate increases in soil temperature are generally related to faster rates of soil organic carbon (SOC) decomposition in Northern ecosystems, but there is evidence that SOC stocks have remained remarkably stable or even increased on the Tibetan Plateau under these conditions. This intriguing observation points to altered soil microbial mediation of carbon-cycling feedbacks in this region that might be related to seasonal warming. This study investigated the unexplained SOC stabilization observed on the Tibetan Plateau by quantifying microbial responses to experimental seasonal warming in a typical alpine meadow. Ecosystem respiration was reduced by 17%–38% under winter warming compared with year-round warming or no warming and coincided with decreased abundances of fungi and functional genes that control labile and stable organic carbon decomposition. Compared with year-round warming, winter warming slowed macroaggregate turnover rates by 1.6 times, increased fine intra-aggregate particulate organic matter content by 75%, and increased carbon stabilized in microaggregates within stable macroaggregates by 56%. Larger bacterial “necromass” (amino sugars) concentrations in soil under winter warming coincided with a 12% increase in carboxyl-C. These results indicate the enhanced physical preservation of SOC under winter warming and emphasize the role of soil microorganisms in aggregate life cycles. In summary, the divergent responses of SOC persistence in soils exposed to winter warming compared to year-round warming are explained by the slowing of microbial decomposition but increasing physical protection of microbially derived organic compounds. Consequently, the soil microbial response to winter warming on the Tibetan Plateau may cause negative feedbacks to global climate change and should be considered in Earth system models.

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