Information

To determine no beating cardiomyocytes from ECG or video recording


I am trying to find data and some method by which I can see and say that there are some cardiomyocytes not working. I have reviewed many arrythmia data where I think I can see much cardiomyocetes there and there which are not beating at all.

Is there any method with available data for the recognisition of cardiomyocytes without beating?

I am particularly interested in the paediatric data. I am using at the moment ECG data after cardiac infarction.

What is the name of this video record? Picture from House season 3 episode 2:


A number of cardiomyocytes is lost during an infarction. Instead, fibrous tissue forms, but it only preserves structural integrity, having no contractile function [1]. Myocardial infarction is an uncommon condition in pediatrics, happening very rare, when embolization occurs due to blood coagulation affections or heart congenital defects [2].

The fibrous tissue has different properties, thus modifying:

  • MDE-MRI images [3]
  • ECG: deep Q wave [4]
  • echocardiography: hypoechoic and hyperdense echoes inside the fibrotic material (the latter compatible with calcium) [5]

That video record is probably about 3D Echocardiography (look here at Video 2 and figure 2).

References:

  1. Yao Sun, Myocardial repair/remodelling following infarction: roles of local factors
  2. Nicola Carano et al., Acute Myocardial Infarction in a Child: Possible Pathogenic Role of Patent Foramen Ovale Associated With Heritable Thrombophilia
  3. Harikrishna Tandri et al., Noninvasive detection of myocardial fibrosis in arrhythmogenic right ventricular cardiomyopathy using delayed-enhancement magnetic resonance imaging
  4. ECGpedia - Pathologic Q Waves
  5. Berenzstein CS et al., Usefulness of echocardiography and doppler echocardiography in endomyocardial fibrosis


Watch the video: Έρευνα σοκ: Όταν πεθαίνουμε, γνωρίζουμε ότι είμαστε νεκροί! (January 2022).